Queen: Joan of England, Queen of Scotland

A shocking aspect of the fictional world of Game of Thrones is the fact that women, even noble women, were treated as chattel, to be swapped from their birth family to a rival family, or among several families, as needs and political ambitions dictated.  Popular rumor indicates that the author of the book based Thrones on the Plantagenet era, either The Anarchy period just before Henry II took the throne in 1254, or the Wars of the Roses.  While it's impossible to generalize about how women were treated on their wedding night, there was only two uses for most noble women and girls of the period, procreation and dynastic alliance.  That did not mean, however, that the men in their family had no familial bonds for them.  It was possible to compartmentalize family feeling and dynastic necessity. 

Joan (1210-1238) the daughter of John of England and Isabella of Angouleme is a case in point.  Almost from the time of her birth, Joan was thought of as a possible wife for the son of old family enemy Phillip II of France.  When those negotiations fell through, John destined her as a bride for Hugh X of Lusignan, Count of La Marche.  Side note, Hugh had originally though to marry Isabella, but her family threw him over for John.  Joan, with the dowry of a princess, was thought of as an appropriate appeasement.  Joan was sent to be reared by Hugh's family until she was old enough to be a suitable bride.  Then, in 1216, when she was still only six years old, King
John died.  Isabella decided to take Hugh up on his offer of marriage after all.  The families decided that Isabella and Joan would switch places, Isabella becoming Hugh's wife and freeing Joan for a match elsewhere.  Protracted negotiations about both women's dowries delayed things until Joan was about ten. 

Joan was sent back to England became the bride of Alexander II of Scotland.  They were married in 1221 and she was Queen of Scots at the ripe age of 11.  Obviously, they didn't live together at first as man and wife, though that did become a possibility once Joan began cycling.  Alexander settled lands from several border towns as Joan's income.  Due to her youth and childless state, Joan didn't have much leverage with Alexander's mother, Ermengarde.  Maybe because of their disparity in ages, the fact that the marriage was childless, or drama with her English family, Joan and Alexander drifted apart and she began spending more time in England, where her brother Henry settled several manors on her as income and a place to stay. 

Then tragedy struck.  In 1238, when she was just 27, Joan fell ill.  Henry and their brother, Richard of Cornwall, hurried to Havering-at-Bower to be present at her death.  She was buried at Tarrant Crawford Abbey in Dorset.  Her death upset Henry III a great deal.  In 1252, Henry ordered a beautiful white gisant or tomb effigy created for Joan's tomb.  This was one of the first such memorial tombs for a queen on English soil.  It was destroyed during the Reformation, though legend says that Joan lies buried in a gold coffin in the ruined churchyard.